At Picterus, we are committed to improving neonatal jaundice screening through rigorous clinical research, supported by peer–reviewed evidence and realworld validation across diverse care pathways, including both clinical and home settings.
Want to learn more about the science and validation behind Picterus Jaundice Pro? Download our latest white paper to explore the clinical background, methodology, and global relevance of our screening solution.
Key findings:
The results suggest that Picterus JP can:
By CW Yoxall. B.Med.Sci., B.M., B.S., M.R.C.P, F.R.C.P.C.H., M.D. Consultant Neonatologist.
The aim of this investigation has been to evaluate the precision of the Picterus JP system in measuring jaundice in the newborn and to assess its potential role as a screening device. The evaluation has been performed on data from 790 newborns across 8 international studies, representing a broad range of clinical settings, populations, and skin tones.
Key findings:
Picterus Jaundice Pro has undergone multiple software generations since its initial clinical validation. Each generation represents a distinct version of the algorithm and user interface, reflecting ongoing development and improvements informed by clinical research and realworld use. When reviewing the clinical evidence, it is therefore important to consider the software version used in each study, as well as the intended use context at the time of evaluation.
Our journey of initial development, validation, and certification is described in the paper by Aune et al. (2023).
Next‑generation model & broader inclusivity
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best performance to date
Expanded clinical use and usability improvements
First CE‑marked medical device
Clinical validation and patented technology
Concept & feasibility research
Over time, the software evolved toward more data driven approaches, including the use of machine learning methods, enabling performance to be refined based on accumulated clinical experience.
Evaluating the Picterus Jaundice Pro App for Neonatal Jaundice Screening by Parents: Prospective Mixed Methods Study
The first CE marked and commercially available generations of the software introduced refinements to image analysis, calibration, and user experience, informed by additional clinical data, expanded use contexts, and feedback from healthcare professionals. This also included an updated version of the Picterus Calibration Card, with added colour swatches to open for a wider variety in colour interpretation.
Advancing neonatal jaundice screening with mHealth: a mixed-methods randomised controlled feasibility study in a resource-limited setting in Mexico.
Validation of a Mobile Health Device for Neonatal Jaundice Screening: A Cross-Sectional Study in a Resource-Limited Setting in Mexico.
Smartphone-based screening of neonatal jaundice in three populations in low and middle-income countries: a cross-sectional study.
Neonatal jaundice detection in low-resource Mexican settings: possibilities and barriers for innovation with mobile health.
Healthcare workers’ perceptions about the use of mobile health technologies in public health facilities in Lagos, Nigeria.
The earliest version of Picterus Jaundice Pro relied on predefined analytical models informed by simulated skin characteristics and reference bilirubin values. The first generation of the app supported foundational feasibility and validation studies and established the clinical potential of smartphone based bilirubin screening. Details are described in the related publications.
This Course will equip you with the essential knowledge and practical skills to confidently assess and manage neonatal jaundice, using tools like Picterus® Jaundice Pro for accurate screening. You’ll also explore clinical guidelines and best practices to ensure that your decisions align with clinical recommendations.
The course is free! Sign up today!